As miRNA-based diagnostics start to enter the clinic, labs should be aware of the range of challenges these tests pose, such as results that are difficult to interpret and the susceptibility of miRNA levels to pre- and post-processing factors.
EDITOR PICK: Induced Pluripotent Stem Cell (iPSC)–Derived Extracellular Vesicles Are Safer and More Effective for Cardiac Repair Than iPSCs
[IMAGE: Characterization of induced pluripotent stem cell–derived extracellular vesicles (iPSC-EVs). Scatter plot of miRNA expression in iPSCs (x axis) and iPSC-EVs (y axis); each dot represents 1 transcript. Data represent mean±SD from 3 independent experiments. PE indicates phycoerythrin.]
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